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1

Synthesis and biological evaluation of novel hybrid chalcone derivatives as vasorelaxant agents

Xiaowu Dong, Lilin Du, Zhichao Pan, Tao Liu, Bo Yang, Yongzhou Hu

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 588 KB

english, 2010

2

Nucleophilic Difluoroalkylation of Isocyanates with Difluoromethyl 2-Pyridyl Sulfone

Li, Shan, Peng, Peng, Wei, Jun, Hu, Yongzhou, Hu, Jinbo, Sheng, Rong

Journal:

Advanced Synthesis & Catalysis

Year:

2015

Language:

english

File:

PDF, 490 KB

english, 2015

3

A convenient synthesis of novel 1,3,4-triaryl-3,4-dihydropyrimidin-2(1H)-ones by cyclization of aromatic isocyanates with β-arylamino-1-phenylpropan-1-ones

Yongzhou Hu, Xiuyang Lu, Na Xue

Journal:

Journal of Heterocyclic Chemistry

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

4

Synthesis and evaluation of water-soluble docetaxel prodrugs-docetaxel esters of malic acid

Wenting Du, Lan Hong, Tongwei Yao, Xiaochun Yang, Qiaojun He, Bo Yang, Yongzhou Hu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 186 KB

english, 2007

5

Synthesis and biological evaluation of 3,4-diaryl-5-aminoisoxazole derivatives

Tao Liu, Xiaowu Dong, Na Xue, Rui Wu, Qiaojun He, Bo Yang, Yongzhou Hu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 416 KB

english, 2009

6

Pharmacophore identification, synthesis, and biological evaluation of carboxylated chalcone derivatives as CysLT1 antagonists

Xiaowu Dong, Li Wang, Xueqin Huang, Tao Liu, Erqing Wei, Lilin Du, Bo Yang, Yongzhou Hu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 916 KB

english, 2010

7

Novel hybrids from lamellarin D and combretastatin A 4 as cytotoxic agents

Li Shen, Xiaochun Yang, Bo Yang, Qiaojun He, Yongzhou Hu

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 445 KB

english, 2010

8

Design and total synthesis of Mannich derivatives of marine natural product lamellarin D as cytotoxic agents

Shen, Li, Xie, Nan, Yang, Bo, Hu, Yongzhou, Zhang, Yongmin

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

9

Identification of novel inhibitors of Aurora A with a 3-(pyrrolopyridin-2-yl)indazole scaffold

Song, Pinrao, Chen, Ming, Ma, Xiaodong, Xu, Lei, Liu, Tao, Zhou, Yubo, Hu, Yongzhou

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 974 KB

english, 2015

10

Design, synthesis and biological evaluation of novel 4-alkynyl-quinoline derivatives as PI3K/mTOR dual inhibitors

Lv, Xiaoqing, Ying, Huazhou, Ma, Xiaodong, Qiu, Ni, Wu, Peng, Yang, Bo, Hu, Yongzhou

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 3.96 MB

english, 2015

11

The Stability and Reactivity of Tri-, Di-, and Monofluoromehtyl/Methoxy/Methylthio Groups on Arenes under Acidic and Basic Conditions

Wang, Lingfei, Wei, Jun, Wu, Ranran, Cheng, Gang, Li, Xinjin, Hu, Jinbo, Hu, Yongzhou, Sheng, Rong

Journal:

Organic Chemistry Frontiers

Year:

2016

Language:

english

File:

PDF, 1.17 MB

english, 2016

12

Discovery of a series of N -(5-(quinolin-6-yl)pyridin-3-yl)benzenesulfonamides as PI3K/mTOR dual inhibitors

Zhang, Jiankang, Lv, Xiaoqing, Ma, Xiaodong, Hu, Yongzhou

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.57 MB

english, 2017

13

Discovery of a novel series of α-terpineol derivatives as promising anti-asthmatic agents: Their design, synthesis, and biological evaluation

Zhu, Wanping, Liu, Xia, Wang, Yuji, Tong, Yeling, Hu, Yongzhou

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 724 KB

english, 2017

14

Synthesis and Antifungal Activity of 2-Aryl-1,2,4-triazolo[1,5-a]pyridine Derivatives

Yun Luo, Yongzhou Hu

Journal:

Archiv der Pharmazie

Year:

2006

Language:

english

File:

PDF, 895 KB

english, 2006

15

Synthesis, Structure and Hypoxic Cytotoxicity of 3-Amino-1,2,4-benzotriazine-1,4-dioxide Derivatives

Faqin Jiang, Qinjie Weng, Rong Sheng, Qing Xia, Qiaojun He, Bo Yang, Yongzhou Hu

Journal:

Archiv der Pharmazie

Year:

2007

Language:

english

File:

PDF, 326 KB

english, 2007

16

Synthesis of Four Natural Prenylflavonoids and Their Estrogen-like Activities

Xiaowu Dong, Yongjian Fan, Lingjun Yu, Yongzhou Hu

Journal:

Archiv der Pharmazie

Year:

2007

Language:

english

File:

PDF, 660 KB

english, 2007

17

Synthesis and In-Vitro Antitumor Activities of Some Mannich Bases of 9-Alkyl-1,2,3,4-tetrahydrocarbazole-1-ones

Jing Chen, Jianshu Lou, Tao Liu, Ru Wu, Xiaowu Dong, Qiaojun He, Bo Yang, Yongzhou Hu

Journal:

Archiv der Pharmazie

Year:

2009

Language:

english

File:

PDF, 438 KB

english, 2009

18

Design, Synthesis, and Biological Evaluation of Prenylated Chalcones as Vasorelaxant Agents

Xiaowu Dong, Jing Chen, Chaoyi Jiang, Tao Liu, Yongzhou Hu

Journal:

Archiv der Pharmazie

Year:

2009

Language:

english

File:

PDF, 618 KB

english, 2009

19

4,5-Diaryl-3-aminopyrazole Derivatives as Analogs of Combretastatin A-4: Synthesis and Biological Evaluation

Tao Liu, Rong Cui, Jing Chen, Jun Zhang, Qiaojun He, Bo Yang, Yongzhou Hu

Journal:

Archiv der Pharmazie

Year:

2011

Language:

english

File:

PDF, 301 KB

english, 2011

20

ChemInform Abstract: Regioselective Synthesis of 2-Arylimidazo[2,1-a]isoquinolines.

Qian Weixing, Hu Yongzhou

Journal:

Year:

2002

File:

PDF, 27 KB

2002

21

Non-steroidal Pregnancy-Terminating Agents: Design, Synthesis and Structure—Activity Relationships of 2-Aryl-1,2,4-triazolo[1,5-a]pyridine.

Tao Liu, Yongzhou Hu

Journal:

Year:

2002

File:

PDF, 28 KB

2002

22

Regioselection in 1,3-Dipolar Cycloadditions of 3-Methylpyridine N-Imide to Aromatic Carbonitriles. Synthesis of 2-Aryl-8-methyl[1,2,4]triazolo[1,5-a]pyridines.

Guolin Zhang, Yongzhou Hu

Journal:

Year:

2003

File:

PDF, 89 KB

2003

23

A Facile Synthesis of 2-Methyl-1,2,3-triazoles.

Beihua Xu, Yongzhou Hu

Journal:

Year:

2003

File:

PDF, 89 KB

2003

24

A Novel and Efficient Strategy for the Preparation of 2,4-Disubstituted-1,2,3-triazoles.

Yun Luo, Yongzhou Hu

Journal:

Year:

2004

File:

PDF, 78 KB

2004

25

One-Pot Facile Synthesis of 1,3,4-Trisubstituted Imidazolin-2-ones

Yunfeng Cheng, Yongzhou Hu

Journal:

Year:

2004

File:

PDF, 18 KB

2004

26

Synthesis of Fully Protected N-Arylglycosylamines and Factors Affecting the Configuration of C1-Substituents of N-Arylglycosylamines.

Wenting Du, Yongzhou Hu

Journal:

Year:

2005

File:

PDF, 22 KB

2005

27

Cleavage of Methyl Ethers of Flavones by Chloroaluminate Ionic Liquid.

Tao Liu, Yongzhou Hu

Journal:

Year:

2005

File:

PDF, 18 KB

2005

28

Novel and Efficient Method to Synthesize N-Benzyl-4-formyl-piperidine.

Rong Sheng, Yongzhou Hu

Journal:

Year:

2005

File:

PDF, 14 KB

2005

29

An Efficient Synthesis of Bis-imidazo[1,2-a]pyridinylmethanes.

Rui Zhang, Yongzhou Hu

Journal:

Year:

2005

File:

PDF, 23 KB

2005

30

Design, Synthesis, and Evaluation of 2-Phenoxy-indan-1-one Derivatives as Acetylcholinesterase Inhibitors.

Rong Sheng, Xiao Lin, Jingya Li, Yanke Jiang, Zhicai Shang, Yongzhou Hu

Journal:

Year:

2005

File:

PDF, 15 KB

2005

31

First Synthesis of 3′-Deoxy Lewisx Pentasaccharide.

Chafika Gourmala, Zhenyuan Zhu, Yun Luo, Bo Tao Fan, Said Ghalem, Yongzhou Hu, Yongmin Zhang

Journal:

Year:

2005

File:

PDF, 8 KB

2005

32

ChemInform Abstract: Synthesis of Novel 1,4-Benzoxazine-2,3-dicarboximides from Maleic Anhydride and Substituted Aromatic Amines.

Peng Wu, Yongzhou Hu

Journal:

Year:

2009

File:

PDF, 36 KB

2009

33

ChemInform Abstract: Microwave-Assisted Mannich Reaction of 2-Hydroxy-chalcones.

Xiaowu Dong, Tao Liu, Jing Chen, Huazhou Ying, Yongzhou Hu

Journal:

Year:

2009

File:

PDF, 44 KB

2009

34

ChemInform Abstract: One-Pot Synthesis of 3-Benzylflavones.

Xiaowu Dong, Tao Liu, Yanping Gao, Jing Chen, Yongzhou Hu

Journal:

Year:

2010

File:

PDF, 28 KB

2010

35

ChemInform Abstract: Novel Hybrids from Lamellarin D and Combretastatin A 4 as Cytotoxic Agents.

Li Shen, Xiaochun Yang, Bo Yang, Qiaojun He, Yongzhou Hu

Journal:

Year:

2010

File:

PDF, 79 KB

2010

36

ChemInform Abstract: Synthesis and Biological Evaluation of New 4β-Anilino-4′-O-demethyl-4-desoxypodophyllotoxin Derivatives as Potential Antitumor Agents.

Li Wang, Fenyan Yang, Xiaochun Yang, Xianghong Guan, Chunqi Hu, Tao Liu, Qiaojun He, Bo Yang, Yongzhou Hu

Journal:

Year:

2011

Language:

english

File:

PDF, 24 KB

english, 2011

37

ChemInform Abstract: Synthesis, Hypoxia-Selective Cytotoxicity of New 3-Amino-1,2,4-benzotriazine-1,4-dioxide Derivatives.

Qing Xia, Ling Zhang, Jun Zhang, Rong Sheng, Bo Yang, Qiaojun He, Yongzhou Hu

Journal:

Year:

2011

File:

PDF, 28 KB

2011

38

ChemInform Abstract: Design, Synthesis, and Biological Evaluation of Novel γ-Carboline Ketones as Anticancer Agents.

Jing Chen, Tao Liu, Rui Wu, Jianshu Lou, Xiaowu Dong, Qiaojun He, Bo Yang, Yongzhou Hu

Journal:

Year:

2011

File:

PDF, 23 KB

2011

39

ChemInform Abstract: 4,5-Diaryl-3-aminopyrazole Derivatives as Analogues of Combretastatin A-4: Synthesis and Biological Evaluation.

Tao Liu, Rong Cui, Jing Chen, Jun Zhang, Qiaojun He, Bo Yang, Yongzhou Hu

Journal:

Year:

2011

File:

PDF, 26 KB

2011

40

ChemInform Abstract: Synthesis and Biological Evaluation of Novel 2-Arylamino-3-(arylsulfonyl) Quinoxalines as PI3Kα Inhibitors.

Yongzhou Hu, et al. et al.

Journal:

Year:

2012

File:

PDF, 30 KB

2012

41

Structure–Activity Relationships of Neuritogenic Gentiside Derivatives

Yan Luo, Kaiyue Sun, Lin Li, Lijuan Gao, Dr. Guangfa Wang, Yuan Qu, Dr. Lan Xiang, Prof. Dr. Ling Chen, Prof. Dr. Yongzhou Hu, Prof. Dr. Jianhua Qi

Journal:

Year:

2011

Language:

english

File:

PDF, 479 KB

english, 2011

42

A facile KF/Al2O3 mediated method for the synthesis of substituted 3-arylchromene-2-thiones

Xiaowei Xu, Yongzhou Hu

Journal:

Journal of Heterocyclic Chemistry

Year:

2006

Language:

english

File:

PDF, 58 KB

english, 2006

43

Synthesis of novel pyrazole-linked norcantharidin derivatives of substituted aromatic amines with efficient 1,3-dipolar cycloaddition

Liping Deng, Yongzhou Hu

Journal:

Journal of Heterocyclic Chemistry

Year:

2006

Language:

english

File:

PDF, 278 KB

english, 2006

44

1,3-dipolar cycloaddition reaction: Synthesis and configuration of norcantharidin derivatives of substituted aromatic amine

Liping Deng, Yongzhou Hu

Journal:

Journal of Heterocyclic Chemistry

Year:

2007

Language:

english

File:

PDF, 416 KB

english, 2007

45

Synthesis and antitumor activities of 2-(substituted)phenyl-1,2,4-triazolo[1,5-a]pyridines

Guolin Zhang, Yongzhou Hu

Journal:

Journal of Heterocyclic Chemistry

Year:

2007

Language:

english

File:

PDF, 232 KB

english, 2007

46

Small molecule agents targeting the p53-MDM2 pathway for cancer therapy

Weisi Wang, Yongzhou Hu

Journal:

Medicinal Research Reviews

Year:

2012

Language:

english

File:

PDF, 494 KB

english, 2012

47

Synthesis and biological evaluation of imidazol-2-one derivatives as potential antitumor agents

Na Xue, Xiaochun Yang, Rui Wu, Jing Chen, Qiaojun He, Bo Yang, Xiuyang Lu, Yongzhou Hu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 526 KB

english, 2008

48

2-Phenoxy-indan-1-one derivatives as acetylcholinesterase inhibitors: A study on the importance of modifications at the side chain on the activity

Yanhong Shen, Rong Sheng, Jing Zhang, Qiaojun He, Bo Yang, Yongzhou Hu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 384 KB

english, 2008

49

Identification of SVM-based classification model, synthesis and evaluation of prenylated flavonoids as vasorelaxant agents

Xiaowu Dong, Yujie Liu, Jingying Yan, Chaoyi Jiang, Jing Chen, Tao Liu, Yongzhou Hu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 383 KB

english, 2008

50

Identification of pharmacophore model, synthesis and biological evaluation of N-phenyl-1-arylamide and N-phenylbenzenesulfonamide derivatives as BACE 1 inhibitors

Wenhai Huang, Haiping Yu, Rong Sheng, Jia Li, Yongzhou Hu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 849 KB

english, 2008